New mRNA activators for Parkinson’s
Research evidence has suggested that in Parkinson’s there is some disruption to a process involved in protein production within cells. This process is known as ‘m6A mRNA methylation’, and activation of this process may protect nerve cells against Parkinson’s.
Laboratory research has shown that supporting and increasing this mRNA methylation process in cells has protective properties. Now, a new project, led by Professors Mart Saarma and Mati Karelson in Finland and Estonia, and funded by Cure Parkinson’s, will assess the ability of different activators of m6A mRNA methylation to protect and repair nerve cells affected by Parkinson’s in the lab.