Dr Simon Stott
Simon is Deputy Director of Research at Cure Parkinson’s. Before this Simon worked as a Parkinson’s research scientist at the University of Cambridge where he conducted both clinical and lab-based research of Parkinson’s. All views/opinions expressed in his blog are solely his own, and may not reflect the views of Cure Parkinson’s or associated parties.
Articles by Dr Simon Stott
A rising tide with liraglutide
A class of diabetes drugs called GLP-1 receptor agonists have exhibited neuroprotective properties in models of Parkinson’s, and a Phase IIb clinical trial produced encouraging. This research has led to a number of parties to start investigating new and old GLP-1 receptor agonists for their potential to slow the progression of […]
GCase: Mutants matter?
Tiny genetic variations in a region of DNA called the GBA gene are associated with an increased risk of developing Parkinson’s. The information in the GBA gene provides the instructions for making an enzyme (called GCase) which is involved with waste disposal inside of cells. Individuals with Parkinson’s who carry a […]
The road ahead: 2022
The first post at the start of each year on the SoPD website tries to provide an overview of where things are in the search for ‘disease modifying’ therapies for Parkinson’s. It is an exercise in managing expectations as well as discussing what research events are scheduled for the next year […]
ADepTing to the UCB-Novartis deal
Alpha synuclein has long been viewed at “Public enemy #1” by the Parkinson’s research community. This sticky, abundant protein starts to cluster (or aggregate) in Parkinson’s. There have been several attempts to reduce levels of the protein floating around outside of cells (using “immunotherapy” approaches) But now clinical research is ramping […]