What does a cure for Parkinson’s look like and how can it be achieved?

We believe there are three research areas focused on curing Parkinson’s; areas that slow, stop and reverse the condition.

1. Stopping Parkinson’s from progressing – Parkinson’s is a progressive disease, which means gradually, over time, the symptoms get worse. Therefore, the first step in correcting Parkinson’s is to identify agents that will slow or stop the condition advancing.

2. Restoring lost function  – Once the disease progression is halted, it will be important to replace the cells and their function that have been lost to the disease. Cell replacement therapies represent a viable approach here.  

3. Protecting the brain cells affected by Parkinson’s – once the progression of the condition has been slowed, it will be important to support and protect surviving cells and provide a nurturing environment for restorative therapies. This will involve identifying neuroprotective treatments.

Cure Parkinson’s is supporting research in all three of these areas. Through our International Linked Clinical Trials (iLCT) programme, we have clinical studies evaluating all aspects of a cure, bringing novel therapies to the clinic for the Parkinson’s community.

At first glance the task ahead of us seems insurmountable, but there is already a huge amount of research being conducted at clinical level across all three components of a cure for Parkinson’s. And through clinical trials supported by Cure Parkinson’s we are seeing the first signs of potentially disease-modifying therapies. It is an exciting time for Parkinson’s research.

Dr Simon Stott, Deputy Director of Research, Cure Parkinson’s