Glossary

Treatments or interventions that affect the underlying pathophysiology of Parkinson's and have a beneficial outcome on the course of the disease.

A small chemical molecule that is one of the brain's neurotransmitters. Among other brain regions, it is found in cells within the substantia nigra. These cells project to the striatum in the basal ganglia. Deficiency of dopamine in the striatum due to the death of cells in the substantia nigra causes symptoms of Parkinsonism.

Neural pathways in the brain which utilise dopamine as their neurotransmitter.

Repurposing generally refers to studying drugs that are already approved to treat one disease or condition to see if they are safe and effective for treating another.