A new case for GCase

Low levels of a protein called GCase is associated with an increased risk of developing Parkinson’s. New understandings of the role of GCase could help to further explain other biological processes observed in the condition.


New clinical trials targeting the LRRK2 gene

LRRK2 is a protein that becomes hyperactive in some people with Parkinson’s, and this is believed to be involved in the progression of their Parkinson’s.


Just a lysosomal enzyme…

About 5% of individuals affected by Parkinson’s carry a genetic variation in a region of their DNA called the GBA1 gene. This area of DNA provides the instructions for making an enzyme called GCase, which is known to be involved in cellular waste disposal. Recently, however, researchers have discovered that GCase […]


Press release

Fundraiser of the Year 2022

11 April 2023 We were delighted to announce the winner of our 2022 Fundraiser of the Year award as the remarkable Simon Cooper. Simon was instrumental in nominating Lloyd’s syndicate AEGIS London as lead sponsor of Cure Parkinson’s Coast-to-Coast-to-Cure cycle challenge in 2019, and in…


Think Loud: Leo Sayer joins industry legends to release charity single for Parkinson’s

Strictly theme co-composer and Procol Harum organist Josh Philips has joined forces with producer Paul Mitchell and legendary music manager Ian Grant to create a new, original track to raise awareness and funds for Parkinson’s