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Anle138b to target the toxic protein in Parkinson’s

In Parkinson’s, a cell protein called alpha-synuclein, which is abundant in dopamine-producing nerve cells, is known to clump together (or aggregate) and it is believed that this process could be toxic. Anle138b is a small molecule that has been designed to inhibit alpha-synuclein aggregation.


Unmasking LRRK2 and GBA

Connecting genetics and biology is complicated. Researchers around the world have struggled to determine what each functional region of DNA is doing individually, let alone in combination with other regions. And sometimes when the output of combinations is examined, the results can be unexpected. Recently, researchers looked at the consequences of […]


Fundraising news

Joyce Cook walks over 300,000 steps for Cure Parkinson’s

On Monday 10 May, 86 year old Joyce Cook from Chorleywood crossed the finish line of her incredible 300,000 step challenge. To mark Parkinson’s Awareness Month, Joyce walked more than 10,000 steps each day for 30 days, beginning on 11 April (World Parkinson’s Day), to…


Something ‘LRRK -ing’ in the data

Over recent years, researchers have been identifying genetic variations associated with an increased risk of developing Parkinson’s. A recent study has thrown further light on the connection between certain genetic risk factors and Parkinson’s progression.


Press release

Joyce Cook walks over 300,000 steps for Cure Parkinson’s

86 year old Chorleywood resident completes 300,000 step challenge for Parkinson’s On Monday 10 May, 86 year old Joyce Cook from Chorleywood crossed the finish line of her incredible 300,000 step challenge. Joyce walked more than 10,000 steps each day for one month, beginning on…